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Condensed Consolidated Balance Sheets (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2014
Dec. 31, 2013
Current assets:    
Cash and cash equivalents $ 172,465 $ 70,790
State research and development tax credit exchange receivable - current 803  
Prepaid expenses and other current assets 20,253 5,485
Total current assets 193,521 76,275
Property and equipment - net 190,923 176,557
State research and development credit exchange receivable 260 298
Other assets 2,114 5,516
Total 386,818 258,646
Current liabilities:    
Accounts payable 17,389 3,860
Accrued expenses and other current liabilities 27,269 21,634
Facility financing obligation   102,300
Senior convertible notes - current 99,120  
Deferred up-front payment from collaboration agreement 150,000  
Total current liabilities 293,778 127,794
Facility financing obligation 72,625  
Senior convertible notes   98,439
Note payable to principal stockholder 49,521 49,521
Other liabilities 11,572 13,605
Total liabilities 427,496 289,359
Commitments and contingencies      
Stockholders' deficit:    
Undesignated preferred stock, $0.01 par value - 10,000,000 shares authorized; no shares issued or outstanding at September 30, 2014 and December 31, 2013      
Common stock, $0.01 par value - 550,000,000 shares authorized at September 30, 2014 and December 31, 2013; 405,469,034 and 369,391,972 shares issued and outstanding at September 30, 2014 and December 31, 2013, respectively 4,055 3,697
Additional paid-in capital 2,413,621 2,261,996
Accumulated other comprehensive loss (11) (4)
Deficit accumulated during the development stage (2,458,343) (2,296,402)
Total stockholders' deficit (40,678) (30,713)
Total $ 386,818 $ 258,646