Exhibit 32.1

 CERTIFICATION OF CHIEF EXECUTIVE OFFICER IN ACCORDANCE WITH SECTION 906 OF THE
                               SARBANES-OXLEY ACT


     In  conjunction  with the annual  report of Sharps  Compliance  Corp.  (the
"Company")  on Form 10-KSB for the years ended June 30, 2005 and 2004,  as filed
with the  Securities  and Exchange  Commission on the date hereof,  I, Burton J.
Kunik,  Chief  Executive  Officer  and  Chairman  of the  Board of the  Company,
certify,  pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906
of the Sarbanes-Oxley Act of 2002, to the best of my knowledge that

     (1)  The Form  10-KSB  report for the years  ended June 30,  2005 and 2004,
          filed with the  Securities  and Exchange  Commission  on September 14,
          2005,  fully complies with the requirements of Section 13 (a) or 15(d)
          of the Securities and Exchange Act of 1934; and

     (2)  The  information  contained  in the Form  10-KSB  report for the years
          ended  June  30,  2005  and  2004  fairly  presents,  in all  material
          respects,  the financial condition and results of operations of Sharps
          Compliance Corp.



      By:  /s/ BURTON J. KUNIK


      Burton J. Kunik
      Chairman of the Board of Directors
      Chief Executive Officer


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