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Note 9 - Accrued Expenses (Tables)
12 Months Ended
Dec. 31, 2019
Notes Tables  
Schedule of Accrued Liabilities [Table Text Block]
    December 31,
    2019   2018
Compensation and related expenses   $
5,830
    $
4,446
 
Professional fees    
3,850
     
1,989
 
Lease liability - current    
1,141
     
 
Income taxes payable    
     
385
 
Research grants    
393
     
400
 
Clinical trial costs    
788
     
577
 
Other    
443
     
349
 
Total   $
12,445
    $
8,146