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Note 8 - Property and Equipment (Tables)
 12 Months Ended
Dec. 31, 2018
Notes Tables  
Property, Plant and Equipment [Table Text Block]
    December 31,
    2018   2017
Equipment and software   $
39,646
     $
37,137
  
Furniture and fixtures    
2,014
      
1,947
  
Leasehold improvements    
33,801
      
31,459
  
Construction in progress    
2,720
      
5,830
  
Subtotal    
78,181
      
76,373
  
Less accumulated depreciation    
(24,070
 )    
(20,190
 )
Total   $
54,111
     $
56,183