Note 15 - Revenue by Product Group, by Significant Customer and by Geographic Location; Geographic Information (Tables)

12 Months Ended

Dec. 31, 2017

Notes Tables

Schedule of Segment Reporting Information, by Segment [Table Text Block]

	Years Ended December 31,
	2017					2016					2015
	Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue
Orthobiologics	$	93,816		87	%	$	89,695		87	%	$	73,247		84	%
Dermal		2,755		3	%		2,759		3	%		2,266		2	%
Surgical		5,262		5	%		5,427		5	%		5,812		7	%
Other		5,950		5	%		5,051		5	%		6,371		7	%
	$	107,783		100	%	$	102,932		100	%	$	87,696		100	%

Schedule of Revenue and Operating Income by Geographical Areas [Table Text Block]

	Years Ended December 31,
	2017					2016					2015
	Total		Percentage of			Total		Percentage of			Total		Percentage of
	Revenue		Revenue			Revenue		Revenue			Revenue		Revenue
Geographic Location:
United States	$	92,905		82	%	$	83,972		81	%	$	76,621		82	%
Europe		12,435		11	%		10,953		11	%		8,756		9	%
Other		8,080		7	%		8,454		8	%		7,622		9	%
Total	$	113,420		100	%	$	103,379		100	%	$	92,999		100	%

Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block]

	Years Ended December 31,
	2017		2016
United States	$	52,828	$	49,140
Italy		3,355		3,156
Total	$	56,183	$	52,296