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Note 18 - Quarterly Financial Data (Unaudited)
 12 Months Ended
Dec. 31, 2017
Notes to Financial Statements  
Quarterly Financial Information [Text Block]
18.
Quarterly Financial Data (Unaudited)
 
    Quarter ended   Quarter ended   Quarter ended   Quarter ended
Year 2017   December 31   September 30   June 30   March 31
Product revenue   $
28,884
     $
27,178
     $
28,340
     $
23,381
  
Total revenue    
29,388
      
27,184
      
33,462
      
23,386
  
Cost of product revenue    
8,716
      
6,250
      
6,315
      
6,083
  
Gross profit on product revenue    
20,168
      
20,928
      
22,025
      
17,298
  
Net income   $
8,067
     $
6,887
     $
11,369
     $
5,493
  
Per common share information:                                
Basic net income per share   $
0.55
     $
0.47
     $
0.78
     $
0.38
  
Basic common shares outstanding    
14,596
      
14,579
      
14,588
      
14,576
  
Diluted net income per share   $
0.53
     $
0.46
     $
0.76
     $
0.37
  
Diluted common shares outstanding    
15,141
      
15,115
      
15,044
      
15,043
  
 
    Quarter ended   Quarter ended   Quarter ended   Quarter ended
Year 2016   December 31   September 30   June 30   March 31
Product revenue   $
28,296
     $
25,783
     $
26,575
     $
22,278
  
Total revenue    
28,726
      
25,789
      
26,581
      
22,283
  
Cost of product revenue    
7,539
      
4,998
      
6,065
      
5,425
  
Gross profit on product revenue    
20,757
      
20,785
      
20,510
      
16,853
  
Net income   $
8,085
     $
8,952
     $
8,615
     $
6,895
  
Per common share information:                                
Basic net income per share   $
0.56
     $
0.61
     $
0.59
     $
0.46
  
Basic common shares outstanding    
14,538
      
14,625
      
14,679
      
14,875
  
Diluted net income per share   $
0.54
     $
0.59
     $
0.57
     $
0.45
  
Diluted common shares outstanding    
14,979
      
15,077
      
15,111
      
15,307