Note 11 - Accrued Expenses - Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Compensation and related expenses	$ 1,818	$ 3,089
Facility construction costs	80	804
Research grants	373	463
Clinical trial costs	565	227
Professional fees	764	802
Deferred rent	118	231
Other	449	880
Total	$ 4,167	$ 6,496