Note 15 - Product Revenue by Product Group (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Orthobiologics [Member]
Product revenue	$ 23,304	$ 19,283	$ 42,891	$ 31,255
Surgical [Member]
Product revenue	1,433	1,647	2,751	3,037
Dermal [Member]
Product revenue	582	303	963	719
Other [Member]
Product revenue	1,256	1,665	2,248	3,402
Product revenue	$ 26,575	$ 22,898	$ 48,853	$ 38,413