Note 16 - Product Revenue by Geographic Location (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
UNITED STATES
Total revenue	$ 76,621	$ 92,259	$ 58,490
Percentage of Revenue	82.00%	87.00%	78.00%
Europe [Member]
Total revenue	$ 8,756	$ 6,215	$ 7,412
Percentage of Revenue	9.00%	6.00%	10.00%
Other Location [Member]
Total revenue	$ 7,622	$ 7,121	$ 9,179
Percentage of Revenue	9.00%	7.00%	12.00%
Total revenue	$ 92,999	$ 105,595	$ 75,081
Percentage of Revenue	100.00%	100.00%	100.00%