Note 16 - Product Revenue by Significant Customers as a Percent of Product Revenues (Details)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Sales Revenue, Goods, Net [Member] | Customer Concentration Risk [Member] | DePuy Mitek Inc [Member]
Concentration Risk, Percentage	72.00%	72.00%	63.00%
Sales Revenue, Goods, Net [Member] | Customer Concentration Risk [Member] | Boehringer [Member]
Concentration Risk, Percentage	5.00%	4.00%	5.00%
Sales Revenue, Goods, Net [Member] | Customer Concentration Risk [Member] | Medtronic [Member]
Concentration Risk, Percentage	3.00%	4.00%	3.00%
Sales Revenue, Goods, Net [Member] | Customer Concentration Risk [Member] | Nordic Pharma [Member]
Concentration Risk, Percentage	2.00%	2.00%	2.00%
Sales Revenue, Goods, Net [Member] | Customer Concentration Risk [Member] | Pharmascience [Member]
Concentration Risk, Percentage	2.00%	2.00%	3.00%
Sales Revenue, Goods, Net [Member] | Customer Concentration Risk [Member]
Concentration Risk, Percentage	84.00%	84.00%	76.00%
Concentration Risk, Percentage	100.00%	100.00%	100.00%