Note 10 - Accrued Expenses - Accrued Expenses (Details) - USD ($)	Jun. 30, 2015	Dec. 31, 2014
Compensation and related expenses	$ 2,260,469	$ 2,791,935
Professional fees	742,319	553,630
Clinical trial costs	421,502	508,042
Research grants	492,001	539,053
Other	525,494	354,866
Total	$ 4,441,785	$ 4,747,526