Note 9 - Accrued Expenses

12 Months Ended

Dec. 31, 2014

Payables and Accruals [Abstract]

Accounts Payable and Accrued Liabilities Disclosure [Text Block]

9. Accrued Expenses

Accrued expenses consist of the following:

	December 31,
	2014		2013
Compensation and related expenses	$	2,791,935	$	2,870,147
Professional fees		553,630		383,231
Clinical trial costs		508,042		882,651
Research grants		539,053		610,498
Restructuring costs		8,384		24,638
Other		346,482		766,716
Total	$	4,747,526	$	5,537,881