Note 8 - Accrued Expenses (Tables)

3 Months Ended

Mar. 31, 2014

Payables and Accruals [Abstract]

Schedule of Accrued Liabilities [Table Text Block]

	March 31, 2014		December 31, 2013
Payroll and benefits	$	1,464,681	$	2,728,616
Clinical trial costs		1,259,914		882,651
Professional fees		321,445		383,231
Research grants		609,878		610,498
Restructuring costs		19,759		24,638
Other		822,029		908,247
Total	$	4,497,706	$	5,537,881