Note 17 - Related Party (Details) (Fidia Farmaceutici S.p.A [Member])	1 Months Ended
Dec. 30, 2009	Dec. 31, 2013	Dec. 31, 2012
Fidia Farmaceutici S.p.A [Member]
Note 17 - Related Party (Details) [Line Items]
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares (in Shares)	1,981,192
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners		0.00%	14.30%

Number of shares of equity interests issued or issuable to acquire entity.

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 805

-SubTopic 30

-Section 50

-Paragraph 1

-Subparagraph (b)(4)

-URI http://asc.fasb.org/extlink&oid=7488404&loc=d3e6927-128479

Name:	us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued
Namespace Prefix:	us-gaap_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration