Note 13 - Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information (Tables)

12 Months Ended

Dec. 31, 2013

Segment Reporting [Abstract]

Schedule of Segment Reporting Information, by Segment [Table Text Block]

	Year Ended December 31,
	2013					2012					2011
	Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue
Orthobiologics	$	55,956,068		78	%	$	49,954,112		74	%	$	39,858,139		64	%
Dermal		1,816,602		3	%		1,384,403		2	%		3,681,166		6	%
Surgical		5,445,715		8	%		5,022,456		7	%		4,976,261		8	%
Ophthalmic		4,656,560		6	%		8,784,011		13	%		10,963,822		18	%
Veterinary		3,898,785		5	%		2,865,187		4	%		2,476,998		4	%
	$	71,773,730		100	%	$	68,010,169		100	%	$	61,956,386		100	%

	Year Ended December 31,
	2013			2012			2011
DePuy Mitek		63	%		61	%		47	%
Boehringer		5	%		4	%		4	%
Bausch & Lomb		5	%		12	%		16	%
Pharmascience/Rivex		3	%		2	%		1	%
Medtronic XoMed		3	%		3	%		6	%
		79	%		82	%		74	%

Schedule of Revenue from External Customers Attributed to Foreign Countries by Geographic Area [Table Text Block]

	Year Ended December 31,
	2013					2012					2011
	Revenue		Percentage of Total Revenue			Revenue		Percentage of Total Revenue			Revenue		Percentage of Total Revenue
United States	$	58,490,142		78	%	$	57,976,667		81	%	$	48,366,140		75	%
Europe		7,411,568		10	%		6,218,890		9	%		10,988,664		17	%
Other		9,179,444		12	%		7,162,948		10	%		5,423,831		8	%
Total	$	75,081,154		100	%	$	71,358,505		100	%	$	64,778,635		100	%

Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block]

	Years Ended December 31,
	2013		2012
United States	$	31,999,468	$	33,792,325
Italy		939,243		1,320,656
Total	$	32,938,711	$	35,112,981