Note 13 - Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information

12 Months Ended

Dec. 31, 2013

Segment Reporting [Abstract]

Segment Reporting Disclosure [Text Block]

13. Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information

Product revenue by product group is as follows:

	Year Ended December 31,
	2013					2012					2011
	Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue
Orthobiologics	$	55,956,068		78	%	$	49,954,112		74	%	$	39,858,139		64	%
Dermal		1,816,602		3	%		1,384,403		2	%		3,681,166		6	%
Surgical		5,445,715		8	%		5,022,456		7	%		4,976,261		8	%
Ophthalmic		4,656,560		6	%		8,784,011		13	%		10,963,822		18	%
Veterinary		3,898,785		5	%		2,865,187		4	%		2,476,998		4	%
	$	71,773,730		100	%	$	68,010,169		100	%	$	61,956,386		100	%

Product revenue by significant customers as a percent of product revenues is as follows:

Percentage of Product Revenue

	Year Ended December 31,
	2013			2012			2011
DePuy Mitek		63	%		61	%		47	%
Boehringer		5	%		4	%		4	%
Bausch & Lomb		5	%		12	%		16	%
Pharmascience/Rivex		3	%		2	%		1	%
Medtronic XoMed		3	%		3	%		6	%
		79	%		82	%		74	%

Total revenue by geographic location in total and as a percentage of total revenue are as follows:

	Year Ended December 31,
	2013					2012					2011
	Revenue		Percentage of Total Revenue			Revenue		Percentage of Total Revenue			Revenue		Percentage of Total Revenue
United States	$	58,490,142		78	%	$	57,976,667		81	%	$	48,366,140		75	%
Europe		7,411,568		10	%		6,218,890		9	%		10,988,664		17	%
Other		9,179,444		12	%		7,162,948		10	%		5,423,831		8	%
Total	$	75,081,154		100	%	$	71,358,505		100	%	$	64,778,635		100	%

The Company recorded licensing, milestone and contract revenue of $3,307,424, $3,348,336 and $2,822,249 for the years ended December 31, 2013, 2012, and 2011, respectively. Substantially all licensing, milestone and contract revenue was derived in the United States for each year presented.

Net long-lived assets, consisting of net property and equipment, are subject to geographic risks because they are generally difficult to move and to effectively utilize in another geographic area in a reasonable time period and because they are relatively illiquid.

Net tangible long-lived assets by principal geographic areas were as follows:

	Years Ended December 31,
	2013		2012
United States	$	31,999,468	$	33,792,325
Italy		939,243		1,320,656
Total	$	32,938,711	$	35,112,981