Product Revenue by Product Group (Detail) (USD $)	3 Months Ended								12 Months Ended
	Dec. 31, 2012	Sep. 30, 2012	Jun. 30, 2012	Mar. 31, 2012	Dec. 31, 2011	Sep. 30, 2011	Jun. 30, 2011	Mar. 31, 2011	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Revenue from External Customer [Line Items]
Product revenue	$ 21,459,124	$ 14,055,440	$ 18,882,277	$ 13,613,328	$ 17,725,546	$ 17,756,000	$ 15,414,681	$ 11,060,159	$ 68,010,169	$ 61,956,386	$ 52,735,730
Percent of product revenue	100.00%				100.00%				100.00%	100.00%	100.00%
Orthobiologics
Revenue from External Customer [Line Items]
Product revenue									49,954,112	39,858,139	30,741,305
Percent of product revenue	73.50%				64.30%				73.50%	64.30%	58.30%
Dermal
Revenue from External Customer [Line Items]
Product revenue									1,384,403	3,681,166	3,564,616
Percent of product revenue	2.00%				5.90%				2.00%	5.90%	6.80%
Surgical
Revenue from External Customer [Line Items]
Product revenue									5,022,456	4,976,261	3,883,444
Percent of product revenue	7.40%				8.10%				7.40%	8.10%	7.30%
Ophthalmic
Revenue from External Customer [Line Items]
Product revenue									8,784,011	10,963,822	11,971,787
Percent of product revenue	12.90%				17.70%				12.90%	17.70%	22.70%
Veterinary
Revenue from External Customer [Line Items]
Product revenue									$ 2,865,187	$ 2,476,998	$ 2,574,578
Percent of product revenue	4.20%				4.00%				4.20%	4.00%	4.90%