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Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information (Tables)

12 Months Ended

Dec. 31, 2012

Product revenue by product group is as follows:

	Year Ended December 31,
	2012					2011					2010
	Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue			Revenue		Percentage of Product Revenue
Orthobiologics	$	49,954,112		73.5	%	$	39,858,139		64.3	%	$	30,741,305		58.3	%
Dermal		1,384,403		2.0	%		3,681,166		5.9	%		3,564,616		6.8	%
Surgical		5,022,456		7.4	%		4,976,261		8.1	%		3,883,444		7.3	%
Ophthalmic		8,784,011		12.9	%		10,963,822		17.7	%		11,971,787		22.7	%
Veterinary		2,865,187		4.2	%		2,476,998		4.0	%		2,574,578		4.9	%
	$	68,010,169		100.0	%	$	61,956,386		100.0	%	$	52,735,730		100.0	%

Percentage of Product Revenue by Significant Customers

Product revenue by significant customers as a percent of product revenues is as follows:

	Percent of Product Revenue
	Year Ended December 31,
	2012	2011	2010
DePuy Mitek	61.2%	47.1%	42.7%
Bausch & Lomb Inc.	11.4%	15.8%	21.2%
Boehringer	4.2%	4.0%	4.9%
Medtronic	3.1%	5.6%	10.2%
Rivex Pharma	2.0%	1.3%	1.5%
	81.9%	73.8%	80.5%

Product Revenue by Geographic Location and Percentage of Total Product Revenue

Revenues by geographic location in total and as a percentage of total revenues are as follows:

	Year Ended December 31,
	2012					2011					2010
	Revenue		Percentage of Total Revenue			Revenue		Percentage of Total Revenue			Revenue		Percentage of Total Revenue
United States	$	57,904,290		81.1	%	$	48,366,140		74.7	%	$	38,313,594		69.0	%
Europe		6,267,830		8.8	%		10,988,664		16.9	%		12,976,985		23.3	%
Other		7,186,385		10.1	%		5,423,831		8.4	%		4,266,015		7.7	%
Total	$	71,358,505		100.0	%	$	64,778,635		100.0	%	$	55,556,594		100.0	%

Net Tangible Long Lived Assets by Principal Geographic Areas

Net tangible long-lived assets by principal geographic areas were as follows:

	Years Ended December 31,
	2012		2011
United States	$	33,792,325	$	34,565,770
Italy		1,320,656		1,904,108
Total	$	35,112,981	$	36,469,878

- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

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