Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information

12 Months Ended

Dec. 31, 2011

Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information

13. Revenue by Product Group, by Significant Customer and by Geographic Region; Geographic Information

Product revenue by product group is as follows:

	Year Ended December 31,
	2011					2010					2009
	Revenue		Percentage of Revenue			Revenue		Percentage of Revenue			Revenue		Percentage of Revenue
Orthobiologics	$	39,858,139		64.3	%	$	30,741,305		58.3	%	$	22,879,899		61.3	%
Dermal		3,681,166		5.9	%		3,564,616		6.8	%		1,471,165		3.9	%
Ophthalmic surgery		10,963,822		17.7	%		11,971,787		22.7	%		10,573,915		28.3	%
Surgical		4,976,261		8.0	%		3,883,444		7.4	%		121,445		0.3	%
Veterinary		2,476,998		4.0	%		2,574,578		4.9	%		2,274,482		6.1	%
	$	61,956,386		100.0	%	$	52,735,730		100.0	%	$	37,320,906		100.0	%

Product revenue by significant customers as a percent of product revenues is as follows:

	Percent of Product Revenue
	Year Ended December 31,
	2011			2010			2009
DePuy Mitek		47.1	%		42.7	%		45.4	%
Bausch & Lomb Inc.		15.8	%		21.2	%		26.6	%
Medtronic		5.6	%		10.2	%		0.0	%
Boehringer		4.0	%		4.9	%		6.1	%
Nycomed / Biomeks		3.5	%		3.3	%		4.4	%
		76.0	%		82.3	%		82.5	%

Revenues by geographic location in total and as a percentage of total revenues are as follows:

	Year Ended December 31,
	2011					2010					2009
	Revenue		Percentage of Revenue			Revenue		Percentage of Revenue			Revenue		Percentage of Revenue
Geographic Location:
United States	$	48,366,140		74.7	%	$	38,313,594		69.0	%	$	30,196,213		75.2	%
Europe		10,988,664		17.0	%		12,976,985		23.4	%		6,536,835		16.3	%
Other		5,423,832		8.4	%		4,266,015		7.7	%		3,402,656		8.5	%
Total	$	64,778,635		100.0	%	$	55,556,594		100.0	%	$	40,135,704		100.0	%

The Company recorded licensing, milestone and contract revenue of $2,822,249, $2,820,864 and $2,814,798 for the years ended December 31, 2011, 2010, and 2009, respectively. Substantially all licensing, milestone and contract revenue was derived in the United States for each year presented.

Net long-lived assets, consisting of net property and equipment, are subject to geographic risks because they are generally difficult to move and to effectively utilize in another geographic area in a reasonable time period and because they are relatively illiquid.

Net tangible long-lived assets by principal geographic areas were as follows:

	Years Ended December 31,
	2011		2010
United States	$	34,565,770	$	34,826,815
Italy		1,904,108		2,154,579
Total	$	36,469,878	$	36,981,394