Exhibit 21.1

SUBSIDIARIES OF

REINSURANCE GROUP OF AMERICA, INCORPORATED

Arch Solutions Group LLC, Missouri Limited Liability Company, 50% owned by Reinsurance Group of America, Incorporated

Arch Solutions Agency LLC, Missouri Limited Liability Company, wholly owned by Arch Solutions Group LLC

Castlewood Financial LLC, Missouri Limited Liability Company, wholly owned by Reinsurance Group of America, Incorporated

Castlewood Reinsurance Company, Missouri corporation, wholly owned by Reinsurance Company of Missouri, Incorporated

Chesterfield Financial Holdings LLC, Delaware Limited Liability Company, wholly owned by Reinsurance Company of Missouri, Incorporated

Chesterfield Reinsurance Company, Missouri corporation, wholly owned by Chesterfield Financial Holdings LLC

Gateway Ridge LLC, Missouri Limited Liability Company, wholly owned by Reinsurance Group of America, Incorporated

Horseshoe Financing LLC, Missouri Limited Liability Company, wholly owned by RGA Worldwide Reinsurance Company, Ltd.

Leidsche Leven Holding B.V., Netherlands limited liability company, wholly owned by Reinsurance Group of America, Incorporated

Leidsche Verzekering Maatschapij N.V., Netherlands corporation, wholly owned by Leidsche Leven Holding B.V.

Malaysian Life Reinsurance Group Berhad, Malaysian corporation, 30% owned by Reinsurance Group of America, Incorporated

Manor Reinsurance, Ltd., Barbados corporation, wholly owned by Reinsurance Group of America, Incorporated

Maroon Financing LLC, Missouri Limited Liability Company, wholly owned by RGA Worldwide Reinsurance Company, Ltd.

Meramec Financing LLC, Iowa Limited Liability Company, wholly owned by RGA Worldwide Reinsurance Company, Ltd.

Newcastle Financial LLC, Missouri Limited Liability Company, wholly owned by Reinsurance Group of America, Incorporated

Parkway Reinsurance Company, Missouri corporation, wholly owned by Reinsurance Company of Missouri, Incorporated

Reinsurance Company of Missouri, Incorporated, Missouri corporation, wholly owned by Reinsurance Group of America, Incorporated

Reinsurance Partners, Inc., Missouri corporation, wholly owned by RGA Reinsurance Company

RGA Americas Reinsurance Company, Ltd., Bermuda corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA Atlantic Reinsurance Company Ltd., Barbados corporation, wholly owned by RGA Americas Reinsurance Company, Ltd.

RGA Australian Holdings Pty Limited, Australian corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA Brazil Serviços Ltda, Brazil limited liability company, 99% owned by Reinsurance Group of America, Incorporated and 1% owned by RGA International Corporation

RGA Capital Limited U.K., United Kingdom private limited company, wholly owned by RGA Holdings Limited

RGA Capital LLC, Missouri Limited Liability Company, wholly owned by Reinsurance Group of America, Incorporated

RGA Enterprise Services Company, Missouri corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA Financial Group, L.L.C., Delaware Limited Liability Company, 55% owned by RGA Reinsurance Company (Barbados) Ltd. and 45% owned by Reinsurance Group of America, Incorporated

RGA Global Reinsurance Company, Ltd., Bermuda private limited corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA Holdings Limited, private limited United Kingdom company, wholly owned by Reinsurance Group of America, Incorporated

RGA International Corporation, Nova Scotia ULC, wholly owned by Reinsurance Group of America, Incorporated

RGA International Division Sydney Office Pty. Limited, Australian Limited Liability Company, wholly owned by RGA International Services Pty Ltd.

RGA International Reinsurance Company Limited, private limited Ireland company, wholly owned by Reinsurance Group of America, Incorporated

RGA International Services Pty Ltd., Australian corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA Life Reinsurance Company of Canada, Federal corporation, wholly owned by RGA Americas Reinsurance Company, Ltd.

RGA Mortgage Loan Servicing LLC, Missouri Limited Liability Company, wholly owned by Reinsurance Group of America, Incorporated

RGA Real Estate Holdings, L.L.C., Missouri Limited Liability Company, wholly owned by RGA Reinsurance Company

RGA Real Estate Investments, L.L.C. , Missouri Limited Liability Company, wholly owned by RGA Reinsurance Company

RGA Reinsurance Company, Missouri corporation, wholly owned by Reinsurance Company of Missouri, Incorporated

RGA Reinsurance Company (Barbados) Ltd., Barbados corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA Reinsurance Company Middle East Limited, Dubai International Finance Centre private limited company, wholly owned by Reinsurance Group of America, Incorporated

RGA Reinsurance Company of Australia Limited, Australian corporation, wholly owned by RGA Australian Holdings Pty Limited

RGA Reinsurance Company of South Africa Limited, South African corporation, wholly owned by RGA South African Holdings (Pty) Ltd.

RGA Services (Singapore) Pte. Ltd., a Singapore Limited Liability Company, wholly owned by Reinsurance Group of America, Incorporated

RGA Services India Private Limited, Indian private limited corporation, 99% owned by Reinsurance Group of America, Incorporated and 1% owned by RGA Holdings Limited

RGA South African Holdings (Pty) Ltd., South African corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA Technology Partners, Inc., Missouri corporation, wholly owned by Reinsurance Group of America, Incorporated

RGA UK Services Limited (f.k.a. RGA Managing Agency Limited), private limited United Kingdom company, wholly owned by RGA Holdings Limited

RGA Worldwide Reinsurance Company, Ltd., Barbados corporation, wholly owned by Reinsurance Group of America, Incorporated

Rockwood Reinsurance Company, a Missouri corporation, wholly owned by Reinsurance Group of America, Incorporated

Timberlake Financial, L.L.C., Delaware Limited Liability Company, wholly owned by Reinsurance Company of Missouri, Incorporated

Timberlake Reinsurance Company II, South Carolina corporation, wholly owned by Timberlake Financial, L.L.C.

Wild Horse Financing LLC, Iowa Limited Liability Company, wholly owned by RGA Worldwide Reinsurance Company, Ltd.