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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (22,645) $ (116,445) $ (67,865)
Adjustments to reconcile loss to net cash used in operating activities:      
Depreciation and amortization 180 23 62
Stock-based compensation 30,917 18,806 13,960
Amortization of debt discount and debt issuance costs 1,644 2,183 2,332
Amortization of intangible asset 679 646 646
Deferred income taxes     11,082
Changes in assets and liabilities:      
Accounts receivable, net (49,907) (21,205) (25,333)
Inventory (18,967) (27,542) (9,753)
Prepaid and other current assets (10,366) 510 6,028
Other long-term assets (900)   567
Accrued interest payable (210) (310) (6,491)
Deferred revenue 136 1,656 1,221
Accounts payable and other current liabilities 65,913 37,602 40,267
Other long-term liabilities (5,840) 9,373 440
Net cash used in operating activities (9,366) (94,703) (32,837)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of furniture, fixtures and equipment (2,478) (58) (12)
Net cash used in investing activities (2,478) (58) (12)
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from issuance of exchangeable debt     30,000
Proceeds from issuance of common stock, net of transaction costs 440,108 264,840  
Proceeds from issuance of common stock under employee stock purchase plan 2,165 1,043  
Proceeds from exercise of stock options, net of transaction costs 24,478 26,402 638
Payment of debt issuance costs     (1,207)
Payment of transaction costs for conversion of preferred stock   (39)  
Repurchase of exchangeable senior notes, including transaction costs     (15,107)
Payment on long-term debt from royalty-bearing instrument (31,652) (14,690) (3,322)
Transaction costs related to exchange of exchangeable senior notes   (121)  
Taxes related to stock-based awards (25,487) (6,184) (2,767)
Net cash provided by financing activities 409,612 271,251 8,235
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH 397,768 176,490 (24,614)
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD 250,727 74,237 98,851
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD 648,495 250,727 74,237
Cash paid during the year for:      
Interest 4,591 21,527 17,241
Income taxes 67 850 $ 1,753
Supplemental disclosure of non-cash transactions:      
Laxdale milestone 8,457    
Initial recognition of operating lease right-of-use asset $ 8,995    
Exchange of exchangeable senior notes into common stock   29,490  
Conversion of Series A Convertible Preferred Stock into common stock   $ 2,514