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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (116,445) $ (67,865) $ (86,350)
Adjustments to reconcile loss to net cash used in operating activities:      
Depreciation and amortization 23 62 138
Loss on sale of fixed assets     48
Allowance for doubtful accounts     12
Stock-based compensation 18,806 13,960 13,613
Amortization of debt discount and debt issuance costs 2,183 2,332 7,783
Amortization of intangible asset 646 646 645
Gain on change in fair value of derivative liabilities     (8,170)
Deferred income taxes   11,082 8,798
Changes in assets and liabilities:      
Accounts receivable, net (21,205) (25,333) (6,171)
Inventory (27,542) (9,753) (1,522)
Prepaid and other current assets 510 6,028 (3,831)
Other long-term assets   567 (567)
Accrued interest payable (310) (6,491) (6,205)
Deferred revenue 1,656 1,221 884
Accounts payable and other current liabilities 37,602 40,267 8,705
Other long-term liabilities 9,373 440 375
Net cash used in operating activities (94,703) (32,837) (71,815)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of equipment (58) (12) (21)
Net cash used in investing activities (58) (12) (21)
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from issuance of exchangeable debt   30,000  
Proceeds from issuance of common stock, net of transaction costs 264,840   64,613
Proceeds from issuance of common stock under employee stock purchase plan 1,043    
Proceeds from exercise of stock options, net of transaction costs 26,402 638 287
Payment of debt issuance costs   (1,207)  
Payment of transaction costs for conversion of preferred stock (39)    
Repurchase of exchangeable senior notes, including transaction costs   (15,107)  
Payment on long-term debt from royalty-bearing instrument (14,690) (3,322)  
Transaction costs related to exchange of exchangeable senior notes (121)   (680)
Taxes paid related to stock-based awards (6,184) (2,767) (1,094)
Net cash provided by financing activities 271,251 8,235 63,126
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH 176,490 (24,614) (8,710)
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD 74,237 98,851 107,561
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD 250,727 74,237 98,851
Cash paid during the year for:      
Interest 21,527 17,241 17,083
Income taxes 850 $ 1,753 1,457
Supplemental disclosure of non-cash transactions:      
Exchange of exchangeable senior notes into common stock 29,490   $ 128,115
Conversion of Series A Convertible Preferred Stock into common stock $ 2,514