Commitments and Contingencies - Additional Information (Detail)	12 Months Ended							1 Months Ended	12 Months Ended			12 Months Ended			12 Months Ended															12 Months Ended		12 Months Ended			1 Months Ended			12 Months Ended
	Dec. 31, 2013 USD ($)	Dec. 31, 2012 USD ($)	Dec. 31, 2011 USD ($)	Dec. 31, 2013 Amr One Hundred One USD ($) Contract	Dec. 31, 2013 Amr One Hundred One Maximum USD ($)	Dec. 31, 2013 Fourth API supplier USD ($)	Dec. 31, 2013 Fourth API supplier Maximum USD ($)	Jul. 31, 2011 Chemport USD ($)	Dec. 31, 2013 Chemport USD ($)	Dec. 31, 2012 Chemport USD ($)	Dec. 31, 2012 Chemport Anticipated investment before the end of 2012 USD ($)	Dec. 31, 2013 Laxdale Limited USD ($)	Dec. 31, 2013 Laxdale Limited GBP (£)	Jul. 26, 2012 Laxdale Limited USD ($)	Dec. 31, 2013 Chemport USD ($)	Dec. 31, 2013 BASF USD ($)	Dec. 31, 2013 Slanhmor USD ($)	Dec. 31, 2013 First Indication for AMR101 Laxdale Limited Potential Marketing Approval 1 USD ($)	Dec. 31, 2013 First Indication for AMR101 Laxdale Limited Potential Marketing Approval 1 GBP (£)	Dec. 31, 2013 First Indication for AMR101 Laxdale Limited Potential Marketing Approval 2 USD ($)	Dec. 31, 2013 First Indication for AMR101 Laxdale Limited Potential Marketing Approval 2 GBP (£)	Dec. 31, 2013 Further Indication for AMR101 Laxdale Limited Potential Marketing Approval 1 USD ($)	Dec. 31, 2013 Further Indication for AMR101 Laxdale Limited Potential Marketing Approval 1 GBP (£)	Dec. 31, 2013 Further Indication for AMR101 Laxdale Limited Potential Marketing Approval 2 USD ($)	Dec. 31, 2013 Further Indication for AMR101 Laxdale Limited Potential Marketing Approval 2 GBP (£)	Dec. 31, 2013 Further Indication for AMR101 Laxdale Limited Maximum USD ($)	Dec. 31, 2013 Further Indication for AMR101 Laxdale Limited Maximum GBP (£)	Dec. 31, 2013 Contract Termination USD ($)	Dec. 31, 2012 Contract Termination USD ($)	Dec. 31, 2013 Groton	Nov. 28, 2011 Groton USD ($) sqft	Dec. 31, 2013 Dublin	Sep. 30, 2011 Dublin USD ($) Y sqft	Sep. 30, 2011 Dublin EUR (€)	May 31, 2013 Bedminster sqft	Dec. 31, 2012 Bedminster sqft	Dec. 31, 2011 Bedminster sqft	Dec. 31, 2013 Bedminster	Jul. 01, 2011 Bedminster sqft
Commitments and Contingencies Disclosure [Line Items]
Office space leased (in square feet)																															4,327		320	320					9,747
Operating lease, term																														3 years
Operating lease, monthly rent																															$ 8,500		$ 3,500	€ 2,700
Operating lease, expiration date																																Oct. 31, 2014						May 31, 2018
Operating lease, renewal option																																	1	1
Additional office space leased (in square feet)																																			10,883	2,601	2,142
Operating lease, rental expense	1,000,000	600,000	500,000
Liabilities for exited lease facilities																												100,000	17,000
Number of signed agreements				2
Development fees committed					500,000		2,300,000
Raw material purchase commitment				1,100,000	5,000,000		15,000,000
Payment made under the agreements				3,100,000		6,200,000									6,900,000	100,000	6,100,000
Minority share equity investment commitment									3,300,000		1,600,000
Cash paid for cost method investment		1,650,000	1,650,000					1,700,000
Investment in supplier sold amount									1,300,000
Carry amount of investment									3,300,000	3,300,000
Potential aggregate stock or cash payment																		12,400,000	7,500,000	12,400,000	7,500,000	8,200,000	5,000,000	8,200,000	5,000,000	16,500,000	10,000,000
Accrued liability payable														11,600,000
Amortization expense													600,000
Cash paid for settlement liability												12,100,000
Currency exchange loss												$ 500,000