Commitments and Contingencies - Additional Information (Detail) $ in Millions	Dec. 31, 2023 USD ($)	Dec. 31, 2023 GBP (£)	Jul. 13, 2022 GBP (£)	Mar. 26, 2021 GBP (£)
Commitments And Contingencies Disclosure [Line Items]
Future contractual purchase obligations without consideration	$ 37.0
Accured estimated liability	8.0
Additional estimated liability	7.8
Minimum
Commitments And Contingencies Disclosure [Line Items]
Estimated liability	8.0
Maximum
Commitments And Contingencies Disclosure [Line Items]
Estimated liability	15.8
Regulatory Approval in Europe
Commitments And Contingencies Disclosure [Line Items]
Additional future contractual purchase obligations without consideration	186.5
Further Indication for AMR101 | Marketing Approval In Europe
Commitments And Contingencies Disclosure [Line Items]
Potential aggregate stock or cash payment | £				£ 7,500,000
Aggregate stock or cash payment upon potential market approval | £			£ 7,500,000
Further Indication for AMR101 | Potential Marketing Approval 1
Commitments And Contingencies Disclosure [Line Items]
Aggregate stock or cash payment upon potential market approval	6.4	£ 5,000,000
Further Indication for AMR101 | Potential Marketing Approval 2
Commitments And Contingencies Disclosure [Line Items]
Aggregate stock or cash payment upon potential market approval	$ 6.4	£ 5,000,000