Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Reconciliation of Total Amounts of Unrecognized Tax Benefits

The following is a reconciliation of the total amounts of unrecognized tax benefits for the years ended December 31, 2022, 2021 and 2020:

In thousands	2022			2021			2020
Beginning uncertain tax benefits	$	22,040		$	24,034		$	26,743
Prior year—increases		—			16			2,428
Prior year—decreases		(9,107	)		(2,248	)		(5,391	)
Current year—increases		5,782			238			254
Ending uncertain tax benefits	$	18,715		$	22,040		$	24,034

Jurisdictions the Company Remains Subject to Tax Examinations

The Company files income tax returns in the United States, Ireland and United Kingdom, or UK. The Company remains subject to tax examinations in the following jurisdictions as of December 31, 2022:

Jurisdiction	Tax Years
United States—Federal	2018-2022
United States—State	2012-2022
Ireland	2018-2022
United Kingdom	2021-2022

Components of Income (Loss) from Operations Before Taxes

The components of income (loss) from operations before taxes were as follows for the years ended December 31, 2022, 2021 and 2020:

In thousands	2022			2021			2020
United States	$	5,358		$	10,222		$	14,915
Ireland and United Kingdom		(112,527	)		(4,368	)		(32,170	)
Other		3,364			5,437			—
Total (loss) / income before taxes	$	(103,805	)	$	11,291		$	(17,255	)

Benefit from Income Taxes

The provision for income taxes shown in the accompanying consolidated statements of operations consists of the following for the years ended December 31, 2022, 2021 and 2020:

In thousands	2022			2021			2020
Current:
United States—Federal	$	562		$	2,690		$	45
United States—State		573			716			700
Foreign		863			156			—
Total current	$	1,998		$	3,562		$	745
Deferred:
United States—Federal		(3,721	)		5,222			1,972
United States—State		284			(3,057	)		1,956
Foreign		(1,646	)		(1,619	)		(26,793	)
Change in valuation allowance		5,083			(546	)		22,865
Total deferred	$	—		$	—		$	—
Provision for income taxes	$	1,998		$	3,562		$	745

Difference between Benefit from Income Taxes and Amount Computed by Applying Statutory Income Tax Rate to Income Before Taxes

The provision for income taxes differs from the amount computed by applying the statutory income tax rate to income before taxes due to the following for the years ended December 31, 2022, 2021 and 2020:

In thousands	2022			2021			2020
Benefits from taxes at statutory rate	$	(25,952	)	$	2,823		$	(4,314	)
Rate differential		9,141			(4,416	)		128
Change in valuation reserves		5,083			(546	)		22,865
Nondeductible employee compensation		2,344			5,249			6,122
Stock option/RSU windfall (shortfall)		3,569			81			(3,262	)
ISO disqualifying disposition windfall		—			(219	)		(253	)
Research and development credits		(958	)		(1,170	)		(6,225	)
Tax return to provision adjustments		424			(8,372	)		(138	)
Net operating loss carryback		—			—			(2,465	)
Foreign exchange		7,859			4,109			(10,852	)
Permanent and other		(1,542	)		863			(4,283	)
Uncertain tax positions		(3,290	)		5,160			3,422
Foreign-derived intangible income		(2,935	)		—			—
Loss of tax attributes		8,255			—			—
Provision for income taxes	$	1,998		$	3,562		$	745

Income Tax Effect of Each Type of Temporary Difference Comprising Net Deferred Tax Asset

The income tax effect of each type of temporary difference comprising the net deferred tax asset as of December 31, 2022 and 2021 is as follows:

In thousands	December 31, 2022			December 31, 2021
Deferred tax assets:
Net operating losses	$	136,862		$	127,378
Stock-based compensation		11,616			8,563
Tax credits		2,639			15,803
Capitalized R&D		4,723			—
Lease liability		2,583			2,348
Other reserves and accrued liabilities		11,895			11,257
Gross deferred tax assets		170,318			165,349
Less: valuation allowance		(165,378	)		(160,295	)
Total deferred tax assets		4,940			5,054
Deferred tax liabilities:
Depreciation and amortization		(3,337	)		(3,404	)
Lease asset		(1,603	)		(1,639	)
Other liabilities		—			(11	)
Total deferred tax liabilities		(4,940	)		(5,054	)
Net deferred tax assets	$	—		$	—

Valuation Allowance

The following table reflects the activity in the valuation allowance for the years ended December 31, 2022 and 2021:

In thousands	2022			2021
Beginning valuation allowance	$	160,295		$	160,841
Increase as reflected in income tax expense		12,942			2,899
Foreign exchange		(7,859	)		(3,445	)
Ending valuation allowance	$	165,378		$	160,295