DESCRIPTION OF BUSINESS (Details) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021	Sep. 30, 2021	Dec. 31, 2020
Description of Business and Basis of Presentation [Line Items]
Accumulated deficit	$ (624,856)	$ (605,643)
Cash and cash equivalents and restricted cash	29,242	$ 38,704	$ 53,126	$ 57,064
CASI China
Description of Business and Basis of Presentation [Line Items]
Cash and cash equivalents and restricted cash	$ 22,200