SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* SPARKLE BYTE LTD (Last) (First) (Middle) P.O. BOX 957 OFFSHORE INCORPORATIONS CENTRE ROAD TOWN (Street) TORTOLA D8 00000 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol CASI Pharmaceuticals, Inc. [ CASI ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 11/13/2018
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	11/13/2018		X		1,699,753	A	$1.69	10,198,518	D(1)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Warrant	$1.69	11/13/2018		X			948,982	04/15/2016	04/15/2019	Common Stock	948,982	$0.125	0	D(1)
Warrant	$1.69	11/13/2018		X			750,771	09/23/2016	09/23/2019	Common Stock	750,771	$0.125	0	D(1)

1. Name and Address of Reporting Person* SPARKLE BYTE LTD (Last) (First) (Middle) P.O. BOX 957 OFFSHORE INCORPORATIONS CENTRE ROAD TOWN (Street) TORTOLA D8 00000 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* SNOW MOON LTD (Last) (First) (Middle) P.O. BOX 957 OFFSHORE INCORPORATIONS CENTRE ROAD TOWN (Street) TORTOLA D8 00000 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* TIANJIN JINGRAN MANAGEMENT CENTER (LIMITED PARTNERSHIP) (Last) (First) (Middle) RM 1704-4920 KUANG SHI GUO JI TOWER A XIANGLUOWAN BUSINESS CTR FREE TRADE ZONE (Street) TIANJIN F4 00000 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* HE XIE AI QI INVESTMENT MANAGEMENT (BEIJING) CO., LTD. (Last) (First) (Middle) ROOM 5835, 5/F, SHENCHANG BUILDING 51 ZHICHUN ROAD, HAIDIAN DISTRICT (Street) BEIJING F4 00000 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Li Jianguang (Last) (First) (Middle) 6/F, TOWER A, COFCO PLAZA 8 JIANGUOMENNEI AVENUE (Street) BEIJING F4 100005 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Lin Dongliang (Last) (First) (Middle) 6/F, TOWER A, COFCO PLAZA 8 JIANGUOMENNEI AVENUE (Street) BEIJING F4 100005 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Yang Fei (Last) (First) (Middle) 34/F SOUTH TOWER, POLY INTERNATIONAL PLZ 1 EAST PAZHOUDADAO (Street) GUANGZHOU F4 510308 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Shong Hugo (Last) (First) (Middle) 6/F, TOWER A, COFCO PLAZA 8 JIANGUOMENNEI AVENUE (Street) BEIJING F4 100005 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. These securities are directly owned by Sparkle Byte Limited ("Sparkle Byte") and may be deemed to be indirectly beneficially owned by the other reporting persons. Snow Moon Limited ("Snow Moon") holds 100% of the equity interest of Sparkle Byte. Tianjin Jingran Management Center (Limited Partnership) ("Tianjin Jingran") holds 100% of the equity interest of Snow Moon. He Xie Ai Qi is the general partner of Tianjin Jingran. Jianguang Li, Dongliang Lin and Hugo Shong are the directors of He Xie Ai Qi. Jianguang Li, Dongliang Lin and Fei Yang hold 12.5%, 43.75% and 43.75% of the equity interest of He Xie Ai Qi, respectively. The filing of this statement by the reporting persons shall not be deemed an admission that such persons are, for purposes of Section 16 of the Securities and Exchange Act of 1934 or otherwise, the beneficial owner of any equity securities covered by this statement.

	/s/ Dongliang Lin, Director, on behalf of Sparkle Byte Limited	11/14/2018
	/s/ Dongliang Lin, Director, on behalf of Snow Moon Limited	11/14/2018
	/s/ Qiuyue Zhong, Representative, on behalf of Tianjin Jingran Management Center (Limited Partnership)	11/14/2018
	/s/ Hugo Shong, Director, on behalf of He Xie Ai Qi Investment Management (Beijing) Co., Ltd.	11/14/2018
	/s/ Jianguang Li	11/14/2018
	/s/ Dongliang Lin	11/14/2018
	/s/ Fei Yang	11/14/2018
	/s/ Hugo Shong	11/14/2018
	** Signature of Reporting Person	Date
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