Weighted

Weighted Average

Aggregate

Average Exercise

Remaining

Intrinsic

Options

Price

Contractual Life

Value

Balance - December 31, 2021

625,565

$

16.12

5.58 years

$

—

Granted

1,728,000

0.58

Exercised

—

Expired

(43,126)

67.81

Forfeited

(14,541)

3.61

Balance - December 31, 2022

2,295,898

3.53

6.44 years

—

Granted

—

Exercised

—

Expired

(429)

404.83

Forfeited

—

Balance - March 31, 2023 - outstanding

2,295,469

$

3.46

6.19 years

$

172,500

Balance - March 31, 2023 - exercisable

636,009

$

10.43

5.06 years

$

18,542

Grant date fair value of options granted – three months ended March 31, 2023

$

—

Weighted average grant date fair value – three months ended March 31, 2023

$

—

Grant date fair value of options granted – year ended December 31, 2022

$

706,264

Weighted average grant date fair value – year ended December 31, 2022

$

0.41