The amount of additional cash payment for license agreement.

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Description related to additional consideration payable.

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Amount of estimated research services cost provided.

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A milestone payment is an authority payment made to a contractor which is linked to the contractor delivering a service or commodity such that, should the agreement be terminated at the point of payment.

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It Represents options to be received common stock shares reporting period.

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The amount of research and development costs incurred for a fixed-price, all payable in quarterly installments.

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The number of shares issued during the period for license agreement.

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Amount of commitment made to pay deferred cash remuneration.

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Commitment made to pay deferred cash remuneration expressed as a percentage of the individual's base salary.

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Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability.

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Weighted average discount rate for operating lease calculated at point in time.

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Amount of cash outflow for fees classified as other.

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Payments of cash to employees, including wages and salaries, during the current period.

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Gross number of share options (or share units) granted during the period.

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License, Collaborative and Employment Agreements and Commitments (Details) - USD ($)									1 Months Ended	12 Months Ended
	Dec. 15, 2022	Mar. 22, 2022	Dec. 23, 2021	Dec. 23, 2020	Aug. 07, 2019	Dec. 19, 2012	Dec. 09, 2012	Nov. 28, 2012	Nov. 30, 2017	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2015
License, Collaborative and Employment Agreements and Commitments
Annual base salary	$ 614,250
Operating Lease weighted average discount rate										8.50%
Operating lease cost										$ 569,000	$ 280,000
Payments for other fees									$ 4,500,000
Licensing Agreements
License, Collaborative and Employment Agreements and Commitments
Annual payments due under license agreement						$ 50,000
Final payment due under license agreement						25,000
Steven A. Shallcross
License, Collaborative and Employment Agreements and Commitments
Annual cash performance bonus				62.00%
Share-based payment award, options, grants in period, gross	475,000			450,000
Cash bonus paid as per employee agreement	$ 385,000
Dr. Sliman
License, Collaborative and Employment Agreements and Commitments
Annual cash performance bonus			62.50%
Share-based payment award, options, grants in period, gross			650,000
Frank Tufaro
License, Collaborative and Employment Agreements and Commitments
Annual cash performance bonus		40.00%
Annual base salary		$ 375,000
Francis Tufaro
License, Collaborative and Employment Agreements and Commitments
Annual cash performance bonus	23.00%
Share-based payment award, options, grants in period, gross	100,000
Annual base salary	$ 393,750
Prev Abr Llc
License, Collaborative and Employment Agreements and Commitments
Additional cash payment for license agreement								$ 235,000
Unregistered shares issued to license agreement								17,858
Additional consideration payable								50% in cash and 50% in our stock
Options to be received common stock shares												18,724
Phase I Clinical Trials
License, Collaborative and Employment Agreements and Commitments
Milestone payment						50,000
Phase III Clinical Trials
License, Collaborative and Employment Agreements and Commitments
Milestone payment						100,000
NDA Submission In US
License, Collaborative and Employment Agreements and Commitments
Milestone payment							$ 250,000
European Medicines Agency Approval
License, Collaborative and Employment Agreements and Commitments
Milestone payment						100,000
Regulatory Approval In Asian Country
License, Collaborative and Employment Agreements and Commitments
Milestone payment						100,000
Clinical Trial Agreement
License, Collaborative and Employment Agreements and Commitments
Estimated research costs					$ 3,200,000
First Year
License, Collaborative and Employment Agreements and Commitments
Research agreement fixed fee						303,287
Second Year
License, Collaborative and Employment Agreements and Commitments
Research agreement fixed fee						316,438
Third Year
License, Collaborative and Employment Agreements and Commitments
Research agreement fixed fee						$ 328,758