Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Cash Flows from Operating Activities:
Net loss	$ (14,268,000)	$ (10,116,000)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation	416,000	350,000
Subsidiary stock issuances to vendor	0	178,000
Depreciation	87,000	201,000
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	174,000	(326,000)
Right of use asset	166,000	141,000
Accounts payable	(363,000)	(1,429,000)
Accrued expenses	1,004,000	(851,000)
Accrued employee benefits	110,000	(67,000)
Lease liability	(216,000)	(249,000)
Net Cash Used in Operating Activities	(12,890,000)	(12,168,000)
Cash Flows from Investing Activities
Purchases of property and equipment	(14,000)	(9,000)
Net Cash Used in Investing Activities	(14,000)	(9,000)
Cash Flows from Financing Activities
Proceeds from "at the market" stock issuance	65,960,000	3,359,000
Proceeds from issuance of common stock for warrant exercises	8,042,000	0
Net Cash Provided by Financing Activities	74,002,000	3,359,000
Net increase (decrease) in cash and cash equivalents	61,098,000	(8,818,000)
Cash and cash equivalents at beginning of year	6,227,000	15,045,000
Cash and cash equivalents at end of year	67,325,000	6,227,000
NONCASH FINANCING ACTIVITIES:
Preferred stock price adjustment	7,402,000	0
Return of SYN Biomics Stock	2,774,000	0
Deemed dividends for accretion of Series B Preferred Stock discount	1,496,000	1,380,000
Right of use assets from operating lease	1,270,000	0
In-kind dividends paid in preferred stock	24,000	254,000
Effect of Warrant exercise price adjustment	0	880,000
Series A Preferred Stock [Member]
NONCASH FINANCING ACTIVITIES:
Conversion of Stock	12,822,000	0
Preferred stock price adjustment	7,402,000	0
Effect of Warrant exercise price adjustment		1,000,000.0
Series B Preferred Stock [Member]
NONCASH FINANCING ACTIVITIES:
Conversion of Stock	2,477,000	2,284,000
Series B Preferred Stock [Member] | Preferred Stock [Member]
Cash Flows from Operating Activities:
Net loss	$ 0	$ 0