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Non-controlling Interest (Details) - USD ($)
3 Months Ended 6 Months Ended
Sep. 05, 2018
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Noncontrolling Interest [Line Items]          
Related Party Transaction, Expenses from Transactions with Related Party $ 441,000        
Research and Development Expense   $ 2,594,000 $ 3,572,000 $ 5,012,000 $ 6,942,000
Synthetic Biomics Inc [Member]          
Noncontrolling Interest [Line Items]          
Additional Number Of Common Stock To Be Issued 2,420,000        
Cedars-Sinai Medical Center [Member]          
Noncontrolling Interest [Line Items]          
Number Of Common Stock To Be Issued 50,000 50,000   50,000  
Research and Development Expense   $ 119,000   $ 174,000  
Fair Value of Shares Issued $ 285,000        
Cedars-Sinai Medical Center [Member] | Synthetic Biomics Inc [Member]          
Noncontrolling Interest [Line Items]          
Number Of Common Stock To Be Held By Related Party 7,480,000 7,480,000   7,480,000  
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners 17.00% 17.00%   17.00%