License, Collaborative and Employment Agreements and Commitments (Details Textual) - USD ($)							1 Months Ended									12 Months Ended
	Sep. 05, 2018	Dec. 04, 2017	Dec. 04, 2015	Aug. 10, 2015	Dec. 05, 2013	Oct. 05, 2012	Dec. 06, 2018	Nov. 30, 2017	Jan. 17, 2017	Nov. 30, 2016	Aug. 31, 2015	Aug. 29, 2015	Apr. 28, 2015	Dec. 19, 2012	Nov. 28, 2012	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2012	Oct. 15, 2018
License, Collaborative and Employment Agreements and Commitments [Line Items]
Line of Credit Facility, Periodic Payment, Interest																$ 381,150
Research and Development Expense	$ 102,000															11,844,000	$ 18,784,000
Operating Leases, Rent Expense																201,000	199,000
Salary and Wage, Officer, Excluding Cost of Good and Service Sold																			$ 385,000
Operating Leases, Future Minimum Payments Due, Next Twelve Months																$ 300,000
Payments for Other Fees								$ 4,500,000
Payments to Acquire in Process Research and Development	321,000																	$ 643,000	$ 424,000
Exchange percentage of unregistered common stock																50.00%
Proceeds from (Repurchase of) Equity																$ 3,000,000	$ 3,000,000
Options To Be Received Common Stock Shares																2,000,000
Shares Issued, Price Per Share																					$ 1.15
Fair Value Of Shares Issued	$ 285,000
Synthetic Biomics Inc [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Additional Number Of Common Stock To Be Issued	2,420,000
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners	(17.00%)
Stock Purchase Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research and Development Expense	$ 36,000,000
Conversion of Stock, Shares Converted												38,572
Conversion of Stock, Shares Issued											38,572	38,572
Channel Collaboration Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Shares, Issued				26,786
Stock Issued				$ 3,000,000
Licensing Agreements [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Payments for Other Fees					$ 150,000
Stock Issued During Period, Shares, New Issues					9,569
Patents [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Payments for Other Fees					$ 220,000
Riley Employment Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Salary and Wage, Officer, Excluding Cost of Good and Service Sold		$ 200,000
Deferred Compensation Arrangement with Individual, Compensation Expense			$ 550,000						$ 385,000							$ 5,397
Deferred Compensation Arrangement with Individual, Cash Awards Granted, Percentage			75.00%						75.00%
Shallcross Employment Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Cash Payment for License Agreement																(8,000)
Deferred Compensation Arrangement with Individual, Compensation Expense							$ 550,000						$ 315,000
Deferred Compensation Arrangement with Individual, Cash Awards Granted, Percentage							75.00%						75.00%
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross													25,714
Jeffrey Riley [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Deferred Compensation Arrangement with Individual, Cash Awards Granted, Percentage																			75.00%
Steven A. Shallcross [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value																			$ 1,900,000
Deferred Compensation Arrangement with Individual, Compensation Expense										$ 346,500
Intrexon [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research and Development Expense																				$ 7,800,000
Stock Issued During Period, Shares, Acquisitions						101,492
Shares Issued, Price Per Share						$ 0.001
Milestone Payment upon First Dosing				$ 2,000,000												2,000,000
Prev Abr Llc [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Additional Cash Payment for License Agreement															$ 235,000
Unregistered Shares Issued to License Agreement															17,858
Additional Consideration Payable															50% in cash and 50% in our stock
Options To Be Received Common Stock Shares																			18,724
Cedars-Sinai Medical Center [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Number Of Common Stock To Be Issued	(50,000)
Cedars-Sinai Medical Center [Member] | Synthetic Biomics Inc [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Additional Number Of Common Stock To Be Issued	(2,420,000)
Number Of Common Stock To Be Held By Related Party	(7,480,000)
December 31, 2014 [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Operating Leases, Future Minimum Payments Due, Next Twelve Months														$ 50,000
December 31, 2015 [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Operating Leases, Future Minimum Payments Due, Next Twelve Months														25,000
Phase I Clinical Trials [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														50,000
Phase III Clinical Trials [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														100,000
NDA Submission In US [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														250,000		$ 2,500,000
European Medicines Agency Approval [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														100,000
Regulatory Approval In Asian Country [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														100,000
First Year [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research Agreement Fixed Fee														303,287
Second Year [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research Agreement Fixed Fee														316,438
Third Year [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research Agreement Fixed Fee														$ 328,758