The additional number of common stock to be issued under stock purchase agreement.

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Amount represents the fair value of shares issued.

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The additional number of common stock to be held by the related party under stock purchase agreement.

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The number of common stock to be issued under stock purchase agreement.

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The number of new shares issued in the conversion of stock in a noncash (or part noncash) transaction. Noncash is defined as transactions during a period that do not result in cash receipts or cash payments in the period. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period.

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The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.

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Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which is directly or indirectly attributable to that ownership interest in subsidiary equity which is not attributable to the parent (that is, noncontrolling interest, previously referred to as minority interest).

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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The equity interest of noncontrolling shareholders, partners or other equity holders in consolidated entity.

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The parent entity's interest in net assets of the subsidiary, expressed as a percentage.

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Amount of Net Income (Loss) attributable to noncontrolling interest.

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Expenses recognized resulting from transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Non-controlling Interest (Details Textual) - USD ($)		1 Months Ended		12 Months Ended
Non-controlling Interest (Details Textual) - USD ($)	Sep. 05, 2018	Aug. 31, 2015	Aug. 29, 2015	Dec. 31, 2018	Dec. 31, 2017
Noncontrolling Interest [Line Items]
Equity Method Investment, Ownership Percentage				83.00%
Net Loss Attributable to Non-controlling Interest				$ (54,000)	$ (318,000)
Stockholders' Equity Attributable to Noncontrolling Interest				(2,909,000)	(1,914,000)
Related Party Transaction, Expenses from Transactions with Related Party	$ 321,000
Research and Development Expense	102,000			$ 11,844,000	18,784,000
Fair Value Of Shares Issued	$ 285,000
Synthetic Biomics Inc [Member]
Noncontrolling Interest [Line Items]
Additional Number Of Common Stock To Be Issued	2,420,000
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners	(17.00%)
SYN Biomics [Member]
Noncontrolling Interest [Line Items]
Equity Method Investment, Ownership Percentage	88.50%			83.00%
Net Loss Attributable to Non-controlling Interest				$ 2,900,000	1,900,000
Noncontrolling Interest, Ownership Percentage by Parent	11.50%		8.50%	17.00%
Consolidation, Eliminations [Member]
Noncontrolling Interest [Line Items]
Net Loss Attributable to Non-controlling Interest					54,000
Dr. Pimentels [Member]
Noncontrolling Interest [Line Items]
Net Loss Attributable to Non-controlling Interest					1,600,000
Dr. Pimentels [Member] \| Consolidation, Eliminations [Member]
Noncontrolling Interest [Line Items]
Stockholders' Equity Attributable to Noncontrolling Interest					$ 505,000
Cedars-Sinai Medical Center [Member]
Noncontrolling Interest [Line Items]
Number Of Common Stock To Be Issued	50,000
Cedars-Sinai Medical Center [Member] \| Synthetic Biomics Inc [Member]
Noncontrolling Interest [Line Items]
Additional Number Of Common Stock To Be Issued	2,420,000
Number Of Common Stock To Be Held By Related Party	7,480,000
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners	(17.00%)
Stock Purchase Agreement [Member]
Noncontrolling Interest [Line Items]
Conversion of Stock, Shares Issued		38,572	38,572
Research and Development Expense	$ 36,000,000