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Selected Quarterly Financial Data (Tables)
12 Months Ended
Dec. 31, 2018
Quarterly Financial Information Disclosure [Abstract]  
Quarterly Financial Information [Table Text Block]
 
 
Quarter Ended
 
 
 
March 31,

2018
 
 
June 30,

2018
 
 
September 30,

2018
 
 
December

31, 2018
 
Loss from operations
 
$
(4,990
)
 
$
(5,003
)
 
$
(4,320
)
 
$
(3,258
)
Net (loss)
 
$
(2,326
)
 
$
(4,214
)
 
$
(3,689
)
 
$
(3,193
)
Net loss per share – basic
 
$
(0.70
)
 
$
(1.05
)
 
$
(0.93
)
 
$
(1.12
)
Net loss per share – dilutive
 
$
(0.70
)
 
$
(1.05
)
 
$
(0.93
)
 
$
(1.12
)
Weighted average common share – basic
 
 
3,673,340
 
 
 
3,683,384
 
 
 
4,028,304
 
 
 
13,442,104
 
Weighted average common share – dilutive
 
 
3,673,340
 
 
 
3,683,384
 
 
 
4,028,304
 
 
 
13,442,104
 
 
 
 
Quarter Ended
 
 
 
March 31,

2017
 
 
June 30,

2017
 
 
September 30,

2017
 
 
December 31,

2017*
 
Loss from operations
 
$
(8,149
)
 
$
(6,475
)
 
$
(5,842
)
 
$
(5,783
)
Net (loss) income
 
$
(3,058
)
 
$
(4,315
)
 
$
(10,930
)
 
$
2,812
 
Net (loss) income per share – basic
 
$
(0.70
)
 
$
(1.05
)
 
$
(4.90
)
 
$
0.76
 
Net (loss) income per share – dilutive
 
$
(0.70
)
 
$
(1.05
)
 
$
(4.90
)
 
$
0.76
 
Weighted average common share – basic
 
 
3,355,636
 
 
 
3,514,435
 
 
 
3,665,134
 
 
 
3,673,340
 
Weighted average common share – dilutive
 
 
3,355,636
 
 
 
3,514,435
 
 
 
3,665,134
 
 
 
3,673,340
 
 
*Net Income due to gain on remeasurement of the warrant liabilities in excess of the quarter to date loss.