Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Operating Costs and Expenses:
General and administrative	$ 1,474	$ 1,705	$ 4,525	$ 5,440
Research and development	2,846	4,137	9,788	15,028
Total Operating Costs and Expenses	4,320	5,842	14,313	20,468
Loss from Operations	(4,320)	(5,842)	(14,313)	(20,468)
Other Income (Expense):
Change in fair value of warrant liability	626	(5,092)	4,064	2,157
Interest income	5	4	20	7
Total Other Income (Expense)	631	(5,088)	4,084	2,164
Net Loss	(3,689)	(10,930)	(10,229)	(18,304)
Net Loss Attributable to Non-controlling Interest	(9)	(8)	(35)	(280)
Net Loss Attributable to Synthetic Biologics, Inc. and Subsidiaries	(3,680)	(10,922)	(10,194)	(18,024)
Series A Preferred Stock Dividends	(61)	(6,901)	(181)	(6,901)
Net Loss Attributable to Common Stock Holders	$ (3,741)	$ (17,823)	$ (10,375)	$ (24,925)
Net Loss Per Share - Basic and Dilutive	$ (0.93)	$ (4.90)	$ (2.73)	$ (7.00)
Weighted average number of shares outstanding during the period - Basic and Dilutive	4,028,304	3,665,134	3,802,812	3,512,868