Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2018

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Share-based Compensation Arrangement by Share-based Payment Award Options and Warrants Vested and Expected to Vest Outstanding and Exercisable [Table Text Block]

The assumptions used for the nine months ended September 30, 2017 are as follows:

Exercise price	$29.05-$30.45
Expected dividends	0%
Expected volatility	90%-92%
Risk free interest rate	1.67%-1.75%
Expected life of option	4.2-4.3 years

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

A summary of stock option activities for the nine months ended September 30, 2018 is as follows:

	Options			Weighted  Average Exercise Price		Weighted Average Remaining Contractual Life	Aggregate Intrinsic Value
Balance - December 31, 2016		332,561		$	61.87	5.49 years	$	194,355
Granted		90,286		$	20.12
Exercised		(11,966	)	$	13.89		$	163,050
Expired		(19,091	)	$	77.46
Forfeited		(32,714	)	$	42.21
Balance - December 31, 2017		359,076		$	53.93	4.60 years	$	1,800
Granted		-		$	-
Exercised		-		$	-		$	-
Expired		(8,124	)	$	53.27
Forfeited		(3,187	)	$	27.28
Balance - September 30, 2018 - outstanding		347,765		$	54.19	3.90 years	$	-
Balance - September 30, 2018 - exercisable		257,985		$	64.63	3.21 years	$	-
Grant date fair value of options granted - September 30, 2018				$	-
Weighted average grant date fair value - September 30, 2018				$	-