<SEC-DOCUMENT>0001144204-18-052016-index.html : 20181002
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<ACCEPTANCE-DATETIME>20181002150129
ACCESSION NUMBER:		0001144204-18-052016
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		12
FILED AS OF DATE:		20181002
DATE AS OF CHANGE:		20181002

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Synthetic Biologics, Inc.
		CENTRAL INDEX KEY:			0000894158
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				133808303
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-227400
		FILM NUMBER:		181100926

	BUSINESS ADDRESS:	
		STREET 1:		9605 MEDICAL CENTER DRIVE
		STREET 2:		SUITE 270
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850
		BUSINESS PHONE:		(734) 332-7800

	MAIL ADDRESS:	
		STREET 1:		9605 MEDICAL CENTER DRIVE
		STREET 2:		SUITE 270
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADEONA PHARMACEUTICALS, INC.
		DATE OF NAME CHANGE:	20081027

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PIPEX PHARMACEUTICALS, INC.
		DATE OF NAME CHANGE:	20061214

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHEFFIELD PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19970730
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Document 1 - file: tv503858_s1a.htm

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<DESCRIPTION>EXHIBIT 1.1
<TEXT>
Document 2 - file: tv503858_ex1-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-3.10
<SEQUENCE>3
<FILENAME>tv503858_ex3-10.htm
<DESCRIPTION>EXHIBIT 3.10
<TEXT>
Document 3 - file: tv503858_ex3-10.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.4
<SEQUENCE>4
<FILENAME>tv503858_ex4-4.htm
<DESCRIPTION>EXHIBIT 4.4
<TEXT>
Document 4 - file: tv503858_ex4-4.htm

</DOCUMENT>
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<SEQUENCE>5
<FILENAME>tv503858_ex5-1a.htm
<DESCRIPTION>EXHIBIT 5.1(A)
<TEXT>
Document 5 - file: tv503858_ex5-1a.htm

</DOCUMENT>
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<TYPE>EX-5.1(B)
<SEQUENCE>6
<FILENAME>tv503858_ex5-1b.htm
<DESCRIPTION>EXHIBIT 5.1(B)
<TEXT>
Document 6 - file: tv503858_ex5-1b.htm

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<TYPE>EX-23.1
<SEQUENCE>7
<FILENAME>tv503858_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 7 - file: tv503858_ex23-1.htm

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Document 10 - file: tv503858_img01.jpg

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Document 11 - file: tv503858_img02.jpg

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Document 12 - file: tv503858_img04.jpg

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