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Selected Balance Sheet Information (Details) - USD ($)
$ in Thousands
Mar. 31, 2017
Dec. 31, 2016
Other Current Assets [Line Items]    
Prepaid clinical research organizations expense $ 2,224 $ 1,677
Prepaid travel and conference expenses 397 295
Prepaid manufacturing expenses 330 0
Prepaid insurances 240 358
Other current assets 175 185
Total $ 3,366 $ 2,515