License, Collaborative and Employment Agreements and Commitments (Details Textual) - USD ($)			1 Months Ended							10 Months Ended	12 Months Ended
	Dec. 04, 2015	Aug. 10, 2015	Dec. 31, 2016	Aug. 31, 2015	Aug. 29, 2015	Aug. 10, 2015	Apr. 28, 2015	Mar. 18, 2015	Feb. 29, 2012	Dec. 31, 2016	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2012
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research and Development Expense											$ 29,109,000	$ 32,906,000	$ 14,489,000
Operating Leases, Rent Expense										$ 285,843	145,000	108,000	77,000
Operating Leases, Future Minimum Payments Due, Next Twelve Months			$ 204,000							204,000	204,000
Prepaid Expense and Other Assets, Current			$ 2,515,000							$ 2,515,000	2,515,000	9,519,000
Payments to Acquire in Process Research and Development											$ 643,000	424,000	$ 293,000
Exchange percentage of unregistered common stock			50.00%							50.00%	50.00%
Proceeds from (Repurchase of) Equity, Total											$ 3,000,000
Stock Purchase Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Conversion of Stock, Shares Converted					1,350,000
Conversion of Stock, Shares Issued				1,350,000	1,350,000
Channel Collaboration Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Shares, Issued		937,500				937,500
Stock Issued		$ 3,000,000				$ 3,000,000
Mark Pimentel [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Common stock Outstanding Percentage			8.50%							8.50%	8.50%
Licensing Agreements [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Payments for Fees											$ 150,000
Stock Issued During Period, Shares, New Issues											334,911
Patents [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Payments for Fees											$ 220,000
Riley Employment Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Deferred Compensation Arrangement with Individual, Compensation Expense	$ 550,000							$ 385,000
Deferred Compensation Arrangement with Individual, Cash Awards Granted, Percentage								75.00%
Shallcross Employment Agreement [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Deferred Compensation Arrangement with Individual, Maximum Contractual Term							2 years
Jeffrey Riley [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value									$ 1,700,000
Officers Compensation									$ 348,000
Options, Granted									750,000
Steven A. Shallcross [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value												1,900,000
Options, Granted							900,000
Deferred Compensation Arrangement with Individual, Compensation Expense			$ 346,500				$ 315,000
Deferred Compensation Arrangement with Individual, Cash Awards Granted, Percentage							75.00%
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent							50.00%
Intrexon [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research and Development Expense														$ 7,800,000
Milestone Payment		27,000,000
Stock Issued During Period, Shares, Acquisitions														3,552,210
Prepaid Expense and Other Assets, Current			$ 2,500,000							$ 2,500,000	$ 2,500,000
Shares Issued, Price Per Share														$ 0.001
Milestone Payment upon First Dosing		$ 2,000,000
Intrexon [Member] | Minimum [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Royalty Revenue, Total												100,000,000
Intrexon [Member] | Maximum [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Royalty Revenue, Total												$ 750,000,000
Prev Abr Llc [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Additional Cash Payment for License Agreement														$ 235,000
Unregistered Shares Issued to License Agreement														625,000
Additional Consideration Payable														50% in cash and 50% in our stock
Options To Be Received Common Stock Shares												655,321
Cedars-Sinai Medical Center [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Common stock Outstanding Percentage			11.50%							11.50%	11.50%
Office Space In Ann Arbor [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Operating Lease Leasing Term														extend the term of the lease to December 31, 2016,
Operating Leases, Future Minimum Payments Due, Next Twelve Months														$ 40,000
Office Space In Rockville [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Operating Lease Leasing Term														sixty-six month operating lease that may be renewed for one additional term of five years
Operating Annual Lease Payments														$ 142,172
December 31, 2014 [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Operating Leases, Future Minimum Payments Due, Next Twelve Months														50,000
December 31, 2015 [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Operating Leases, Future Minimum Payments Due, Next Twelve Months														25,000
Phase I Clinical Trials [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														50,000
Phase III Clinical Trials [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														100,000
NDA Submission In US [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														250,000
European Medicines Agency Approval [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														100,000
Regulatory Approval In Asian Country [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Milestone Payment														$ 100,000
IND Milestone Event [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Registration Payment Arrangement, Settlement Alternatives														The Company also agreed upon the filing of an IND application with the FDA for a Synthetic Product, or alternatively the filing of the first equivalent regulatory filing with a foreign regulatory agency (both as applicable, the IND Milestone Event), to pay Intrexon either (i) $2.0 million in cash, or (ii) that number of shares of Common Stock (the IND Milestone Shares) having a fair market value equaling $2.0 million where such fair market value is determined using published market data of the share price for Common Stock at the close of market on the business day immediately preceding the date of public announcement of attainment of the IND Milestone Event.
Approval Milestone Event [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Registration Payment Arrangement, Settlement Alternatives														Upon the first to occur of either first commercial sale of a Synthetic Product in a country or the granting of the regulatory approval of that Synthetic Product (both as applicable, the Approval Milestone Event), the Company agreed to pay to Intrexon either (i) $3.0 million in cash, or (ii) that number of shares of Common Stock (the Approval Milestone Shares) having a fair market value equaling $3.0 million where such fair market value is determined using published market data of the share price for Common Stock at the close of market on the business day immediately preceding the date of public announcement of attainment of the Approval Milestone Event.
Field Expansion Fee [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Registration Payment Arrangement, Settlement Alternatives														The Field Expansion Fee must be paid completely in either Common Stock or cash, and will comprise either (i) $2.0 million in cash for each target in excess of three total that the Company elects, or (ii) that number of shares of Common Stock (the Field Expansion Fee Shares) having a fair market value equaling $2.0 million for each such target that the Company elects in excess of three where such fair market value is determined using published market data establishing the volume-weighted average price for a share of Common Stock over the 30 day period immediately preceding the date of the Field Expansion Fee Closing
First Year [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research Agreement Fixed Fee			$ 303,287							$ 303,287	$ 303,287
Second Year [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research Agreement Fixed Fee			316,438							316,438	316,438
Third Year [Member]
License, Collaborative and Employment Agreements and Commitments [Line Items]
Research Agreement Fixed Fee			$ 328,758							$ 328,758	$ 328,758