Consolidated Statements of Operations (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Operating Costs and Expenses:
General and administrative	$ 1,814	$ 1,258	$ 2,936	$ 2,380
Research and development	2,837	1,203	5,554	2,321
Total Operating Costs and Expenses	4,651	2,461	8,490	4,701
Loss from Operations	(4,651)	(2,461)	(8,490)	(4,701)
Other Income (Expense):
Interest income	0	10	1	21
Other income (expense)	95	(46)	95	(45)
Total Other Income (Expense)	95	(36)	96	(24)
Net Loss	(4,556)	(2,497)	(8,394)	(4,725)
Net Loss Attributable to Non-controlling Interest	0	0	0	0
Net Loss Attributable to Synthetic Biologics, Inc. and Subsidiaries	$ (4,556)	$ (2,497)	$ (8,394)	$ (4,725)
Net Loss Per Share - Basic and Dilutive (in dollars per share)	$ (0.08)	$ (0.06)	$ (0.14)	$ (0.11)
Net Loss Per Share Attributable to Synthetic Biologics, Inc. and Subsidiaries (in dollars per share)	$ (0.08)	$ (0.06)	$ (0.14)	$ (0.11)
Weighted average number of shares outstanding during the period - Basic and Dilutive (in shares)	58,453,528	44,654,414	58,348,153	44,628,051