Consolidated Statements of Operations (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2014	Mar. 31, 2013
Operating Costs and Expenses:
General and administrative	$ 1,122	$ 1,122
Research and development	2,717	1,118
Total Operating Costs and Expenses	3,839	2,240
Loss from Operations	(3,839)	(2,240)
Other Income:
Interest income	1	11
Other income	0	1
Total Other Income	1	12
Net Loss	(3,838)	(2,228)
Net Loss Attributable to Non-controlling Interest	0	0
Net Loss Attributable to Synthetic Biologics, Inc. and Subsidiaries	$ (3,838)	$ (2,228)
Net Loss Per Share - Basic and Dilutive (in dollars per share)	$ (0.07)	$ (0.05)
Net Loss Per Share Attributable to Synthetic Biologics, Inc. and Subsidiaries (in dollars per share)	$ (0.07)	$ (0.05)
Weighted average number of shares outstanding during the period - Basic and Dilutive (in shares)	58,324,260	44,601,396