Summary of Significant Accounting Policies - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018	Sep. 05, 2018	Aug. 29, 2015
Summary of Significant Accounting Policies [Line Items]
Depreciation, Depletion and Amortization	$ 201,000	$ 240,000
Cash and Cash Equivalents, at Carrying Value.	$ 6,227,000	15,045,000	$ 28,918,000
Equity Method Investment, Ownership Percentage	83.00%
Accrued Liabilities	$ 700,000	700,000
Prepaid Expense	470,000	48,000
preferred stock accrued dividends	254,000	248,000
Net Loss Attributable to Non-controlling Interest	$ (73,000)	$ (77,000)
Preferred Stock Shares Converted	3,665	1,523
Right of use asset	$ 279,000	$ 419,000
Operating Lease Liability	287,000	249,000
Series A and Series B Preferred Stock [Member]
Summary of Significant Accounting Policies [Line Items]
Net Loss Attributable to Non-controlling Interest	$ 100,000	$ 100,000
Series B Preferred Stock [Member]
Summary of Significant Accounting Policies [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	3,454,783	6,641,736
preferred stock accrued dividends	$ 1,380,000	$ 525,000
Net Loss Attributable to Non-controlling Interest	0	0
Accretion of preferred discount	$ 1,400,000	$ 525,000
Series A Preferred Stock [Member]
Summary of Significant Accounting Policies [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	678,258	664,798
preferred stock accrued dividends	$ 254,000	$ 248,000
Accretion of preferred discount			$ 6,900,000
Warrant [Member]
Summary of Significant Accounting Policies [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	18,000,713	18,714,999
Options [Member]
Summary of Significant Accounting Policies [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	3,997,418	2,502,012
Money Market Accounts [Member]
Summary of Significant Accounting Policies [Line Items]
Cash and Cash Equivalents, at Carrying Value.	$ 114,000	$ 98,000
SYN Biomics [Member]
Summary of Significant Accounting Policies [Line Items]
Equity Method Investment, Ownership Percentage	83.00%			88.50%
Noncontrolling Interest, Ownership Percentage by Parent	17.00%			11.50%	8.50%
Net Loss Attributable to Non-controlling Interest	$ 2,800,000	$ 2,900,000