Summary of Significant Accounting Policies - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Jan. 01, 2019	Sep. 05, 2018	Dec. 31, 2017	Aug. 29, 2015
Summary of Significant Accounting Policies [Line Items]
Depreciation, Depletion and Amortization	$ 240,000	$ 272,000
Cash and Cash Equivalents, at Carrying Value.	$ 15,045,000	28,918,000			$ 17,116,000
Equity Method Investment, Ownership Percentage	83.00%
Accrued Liabilities	$ 700,000	700,000
Prepaid Expense	48,000	0
preferred stock accrued dividends	248,000	243,000
Net Loss Attributable to Non-controlling Interest	$ (77,000)	$ (54,000)
Preferred Stock Shares Converted	1,523	6,562
Right of Use Asset	$ 419,000	$ 0	$ 537,000
Operating Lease Liability	$ 249,000	$ 0	$ 939,000
Series B Preferred Stock [Member]
Summary of Significant Accounting Policies [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	6,641,736	7,966,057
preferred stock accrued dividends	$ 525,000	$ 11,681,000
Accretion of Preferred Stock Deemed Dividend		9,200,000
Net Loss Attributable to Non-controlling Interest	0	0
Accretion of preferred discount	525,000	2,500,000
Series A Preferred Stock [Member]
Summary of Significant Accounting Policies [Line Items]
preferred stock accrued dividends	$ 248,000	$ 243,000
Accretion of preferred discount					$ 6,900,000
Warrant [Member]
Summary of Significant Accounting Policies [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	18,714,999	18,915,850
Options [Member]
Summary of Significant Accounting Policies [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	2,502,012	938,982
Money Market Accounts [Member]
Summary of Significant Accounting Policies [Line Items]
Cash and Cash Equivalents, at Carrying Value.	$ 98,000	$ 98,000
SYN Biomics [Member]
Summary of Significant Accounting Policies [Line Items]
Equity Method Investment, Ownership Percentage	83.00%			88.50%
Noncontrolling Interest, Ownership Percentage by Parent	17.00%			11.50%		8.50%
Net Loss Attributable to Non-controlling Interest	$ 2,900,000	$ 2,900,000