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Stock-Based Compensation - Summary of stock option activity (Details) - Stock Option [Member] - USD ($)
9 Months Ended 12 Months Ended
Sep. 30, 2019
Dec. 31, 2018
Dec. 31, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Options, Beginning Balance 938,982 359,076  
Options, Granted   671,500  
Options, Expired (68,173) (78,667)  
Options, Forfeited (67,232) (12,927)  
Options, Ending Balance 803,577 938,982 359,076
Options, Exercisable 330,470    
Weighted Average Exercise Price, Beginning Balance $ 15.18 $ 53.93  
Weighted Average Exercise Price, Granted   0.69  
Weighted Average Exercise Price, Expired 64.76 67.02  
Weighted Average Exercise Price, Forfeited 5.95 23.72  
Weighted Average Exercise Price, Ending Balance 11.74 $ 15.18 $ 53.93
Weighted Average Exercise Price, Exercisable $ 26.77    
Weighted Average Remaining Contractual Life, Balance Outstanding 5 years 7 months 21 days 6 years 2 months 9 days 4 years 7 months 6 days
Weighted Average Remaining Contractual Life, Exercisable 4 years 10 months 21 days    
Aggregate Intrinsic Value, Ending Balance $ 0 $ 0 $ 1,800
Aggregate Intrinsic Value, Exercisable 0    
Grant date fair value of options granted $ 0 $ 301,000  
Weighted average grant date fair value $ 0 $ 0.45