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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 MFo6vzEapeH+XfPv4cuX2ZvferEBcXFerlsB7cHLLR2dTFrNYThFhEKsuSDEox2M
 hHg5WjN2HP5VNyMmjloGSA==

<SEC-DOCUMENT>0001388833-07-000001.txt : 20070409
<SEC-HEADER>0001388833-07-000001.hdr.sgml : 20070409
<ACCEPTANCE-DATETIME>20070409170654
ACCESSION NUMBER:		0001388833-07-000001
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070405
FILED AS OF DATE:		20070409
DATE AS OF CHANGE:		20070409

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VENTANA MEDICAL SYSTEMS INC
		CENTRAL INDEX KEY:			0000893160
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				942976937
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1910 INNOVATION PARK DRIVE
		CITY:			TUCSON
		STATE:			AZ
		ZIP:			85755
		BUSINESS PHONE:		800-227-2155

	MAIL ADDRESS:	
		STREET 1:		1910 INNOVATION PARK DRIVE
		CITY:			TUCSON
		STATE:			AZ
		ZIP:			85755

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Mehren Lawrence
		CENTRAL INDEX KEY:			0001388833

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-20931
		FILM NUMBER:		07756876

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		800-227-2155

	MAIL ADDRESS:	
		STREET 1:		1910 E. INNOVATION PARK DRIVE
		CITY:			TUCSON
		STATE:			AZ
		ZIP:			85755
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2007-04-05</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000893160</issuerCik>
        <issuerName>VENTANA MEDICAL SYSTEMS INC</issuerName>
        <issuerTradingSymbol>vmsi</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001388833</rptOwnerCik>
            <rptOwnerName>Mehren Lawrence</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1910 E. INNOVATION PARK DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>TUCSON</rptOwnerCity>
            <rptOwnerState>AZ</rptOwnerState>
            <rptOwnerZipCode>85755</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Sr.VP &amp; CFO( Effective 5-1-07)</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <ownerSignature>
        <signatureName>Leslie Oaks as attorney in fact for Lawrence Mehren</signatureName>
        <signatureDate>2007-04-09</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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