EXHIBIT 32.1

                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                       AS ADOPTED PURSUANT TO SECTION 906
                        OF THE SARBANES-OXLEY ACT OF 2002

         In connection with the Quarterly Report of Perma-Fix Environmental
Services, Inc. ("PESI") on Form 10-Q for the quarter ended March 31, 2006, as
filed with the Securities and Exchange Commission on the date hereof (the "Form
10-Q"), I Dr. Louis F. Centofanti, Chief Executive Officer of the Company,
certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906
of the Sarbanes-Oxley Act of 2002, that:

         (1) The Form 10-Q fully complies with the requirements of Section 13(a)
         or 15(d) of the Securities Exchange Act of 1934 (15 U.S.C. Section 78m
         or Section 78o(d)); and

         (2) The information contained in the Form 10-Q fairly presents, in all
         material respects, the financial condition and results of operations of
         the Company.

Dated: May 9, 2006

                                                         /s/ Louis F. Centofanti
                                                         -----------------------
                                                         Dr. Louis F. Centofanti
                                                         President and
                                                         Chief Executive Officer

This certification is furnished to the Securities and Exchange Commission solely
for purpose of 18 U.S.C. Section 1350 subject to the knowledge standard
contained therein, and not for any other purpose.