CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
Revenues:
Product sales, net	$ 740	$ 2,021	$ 2,394	$ 4,437
License and contract revenue	224	37,513	2,398	37,851
Total revenues	964	39,534	4,792	42,288
Operating costs and expenses:
Cost of product sold	831	252	1,204	599
Research and development	18,404	16,528	55,195	42,725
Selling, general and administrative	13,682	12,563	38,603	43,104
Other operating expense		2,719	253	2,719
Total operating costs and expenses	32,917	32,062	95,255	89,147
Income (loss) from operations	(31,953)	7,472	(90,463)	(46,859)
Non-operating income (expense):
Interest expense	(1,288)	(472)	(2,379)	(1,403)
Amortization of debt discount and issuance costs	(40)	(185)	(351)	(547)
Foreign exchange loss	(18)	(2,455)	(561)	(2,621)
Other non-operating income (expense)	203		(993)	(885)
Total non-operating expense, net	(1,143)	(3,112)	(4,284)	(5,456)
Net income (loss) before noncontrolling interest	(33,096)	4,360	(94,747)	(52,315)
Noncontrolling interest	504	243	962	517
Net income (loss)	$ (32,592)	$ 4,603	$ (93,785)	$ (51,798)
Net income (loss) per common share:
Basic	$ (0.19)	$ 0.03	$ (0.54)	$ (0.36)
Diluted	$ (0.19)	$ 0.03	$ (0.54)	$ (0.36)
Shares used in calculation of earnings (loss) per common share:
Basic	176,004	145,138	175,143	143,920
Diluted	176,004	147,097	175,143	143,920