Exhibit 12.1

STATEMENT RE: COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

(in thousands)

	Year Ended December 31,
	2003		2002		2001		2000		1999
Net loss	(130,031	)	(49,903	)	(80,273	)	(51,929	)	(36,280	)
Add: fixed charges	10,706		12,335		6,467		729		711
Earnings as defined	(119,325	)	(37,568	)	(73,806	)	(51,200	)	(35,569	)
Fixed charges:
Interest expensed and capitalized	9,326		11,240		5,988		544		502
Estimated interest component of rent	1,380		1,095		479		185		209
Total fixed charges	10,706		12,335		6,467		729		711
Ratio of earnings to fixed charges	(1	)	(1	)	(1	)	(1	)	(1	)

(1) Earnings (as defined) for the period were insufficient to cover fixed charges by an amount equal to the net loss for the period.