CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Revenues:
Total revenues	$ 640	$ 10,846
Operating costs and expenses:
Research and development	5,172	9,685
Selling, general and administrative	5,206	5,497
Restructuring expenses	794	0
Total operating costs and expenses	11,172	15,182
Loss from operations	(10,532)	(4,336)
Non-operating income (expense):
Interest income	380	0
Interest expense	(294)	(288)
Amortization of debt discount and issuance costs	(130)	(134)
Foreign exchange (loss) gain	(238)	723
Total non-operating (expense) income, net	(282)	301
Net loss before noncontrolling interest	(10,814)	(4,035)
Noncontrolling interest	0	14
Net loss	(10,814)	(4,021)
Deemed dividends on preferred stock	0	(80)
Net loss attributable to common stockholders	$ (10,814)	$ (4,101)
Basic and diluted net loss per common share (in dollars per share)	$ (0.19)	$ (0.08)
Shares used in calculation of basic and diluted net loss per common share (in shares)	57,973	50,312