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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 L/3EVvXV7etyjLbut2MKQSyK7mroYrSMhF3OOif/5j2Deea/95u7PoEUP4BnUB1C
 6HeLMlzbMlZu7VB/FBh/UQ==

<SEC-DOCUMENT>0001263259-03-000004.txt : 20030916
<SEC-HEADER>0001263259-03-000004.hdr.sgml : 20030916
<ACCEPTANCE-DATETIME>20030916160254
ACCESSION NUMBER:		0001263259-03-000004
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030909
FILED AS OF DATE:		20030916

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NPS PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000890465
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				870439579
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		420 CHIPETA WAY STE 240
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84108-1256
		BUSINESS PHONE:		8015834939

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			STILLER CALVIN
		CENTRAL INDEX KEY:			0001263259

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23272
		FILM NUMBER:		03897727

	BUSINESS ADDRESS:	
		STREET 1:		148 FULLARTEN STREET
		STREET 2:		#2006
		CITY:			LONDON ONTARIO CANADA
		STATE:			A6
		ZIP:			N6A 5P3
		BUSINESS PHONE:		4162134694
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>
    <schemaVersion>X0201</schemaVersion>

    <documentType>4/A</documentType><periodOfReport>2003-09-09</periodOfReport><dateOfOriginalSubmission>2003-09-11</dateOfOriginalSubmission>
    <issuer>
        <issuerCik>0000890465</issuerCik>
        <issuerName>NPS PHARMACEUTICALS INC</issuerName>
        <issuerTradingSymbol>NPSP</issuerTradingSymbol></issuer><reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001263259</rptOwnerCik>
            <rptOwnerName>STILLER CALVIN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>420 CHIPETA WAY</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>SALT LAKE CITY</rptOwnerCity>
            <rptOwnerState>UT</rptOwnerState>
            <rptOwnerZipCode>84108</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
<isDirector>1</isDirector><isOfficer>0</isOfficer><isTenPercentOwner>0</isTenPercentOwner><isOther>0</isOther></reportingOwnerRelationship></reportingOwner><nonDerivativeTable><nonDerivativeTransaction><securityTitle><value>Common Stock</value></securityTitle><transactionDate><value>2003-09-09</value></transactionDate><deemedExecutionDate><value>2003-09-09</value></deemedExecutionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>S</transactionCode><equitySwapInvolved>0</equitySwapInvolved><footnoteId id="F1"/></transactionCoding><transactionAmounts><transactionShares><value>20000</value></transactionShares><transactionPricePerShare><value>32.00</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>D</value></transactionAcquiredDisposedCode></transactionAmounts><postTransactionAmounts><sharesOwnedFollowingTransaction><value>219043</value><footnoteId id="F2"/></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwner
ship><value>I</value></directOrIndirectOwnership><natureOfOwnership><value>Canadian Medical Discoveries Fund Inc.</value></natureOfOwnership></ownershipNature></nonDerivativeTransaction><nonDerivativeTransaction><securityTitle><value>Common Stock</value></securityTitle><transactionDate><value>2003-09-11</value></transactionDate><deemedExecutionDate><value>2003-09-11</value></deemedExecutionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>S</transactionCode><equitySwapInvolved>0</equitySwapInvolved><footnoteId id="F1"/></transactionCoding><transactionAmounts><transactionShares><value>24000</value></transactionShares><transactionPricePerShare><value>32.00</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>D</value></transactionAcquiredDisposedCode></transactionAmounts><postTransactionAmounts><sharesOwnedFollowingTransaction><value>195043</value><footnoteId id="F2"/></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrInd
irectOwnership><value>I</value></directOrIndirectOwnership><natureOfOwnership><value>Canadian Medical Discoveries Fund Inc.</value></natureOfOwnership></ownershipNature></nonDerivativeTransaction><nonDerivativeHolding><securityTitle><value>Common Stock</value></securityTitle><postTransactionAmounts><sharesOwnedFollowingTransaction><value>4200</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>D</value></directOrIndirectOwnership><natureOfOwnership><value/></natureOfOwnership></ownershipNature></nonDerivativeHolding></nonDerivativeTable><footnotes><footnote id="F1">This transaction was executed under a Rule 10b5-1 trading plan.</footnote><footnote id="F2">The reporting person disclaims beneficial ownership of these securities except to the extent of the person's pecuniary interest in the securities, if any.</footnote></footnotes><remarks/><ownerSignature><signatureName>James U. Jensen</signatureName><signatureDate>2003-09-16</signatureDate></ow
nerSignature></ownershipDocument>

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</TEXT>
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</SEC-DOCUMENT>
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